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THE SWARTS LAB – Wageningen University, Laboratory of Biochemistry

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Research highlights May 15, 2025 "Cyanobacterial Argonautes and Cas4 family nucleases cooperate to interfere with invading DNA" published in Molecular Cell. We investigated the function, structure, and mechanisms of APACE systems (Long-A pAgos associated with Argonaute-associated Cas4-like enzymes (ACE), found in cyanobacteria. We show that ACE1 can generate small DNA guides for its associated long-A…

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Websiteswartslab.org ↗
Site languageBritish English
Last read20 Sep 2026
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